WebEver since nitric oxide (NO) was discoverd to be a powerful endothelium-derived vasorelaxing substance, a number of methods have been developed to investigate the role of NO in the vasodilatory proce WebVasodilation is the archetypal function of the endothelial cell and the discovery of paracrine-dependent vasorelaxation by endothelium-derived production of the gaseous mediator nitric oxide (NO) was revolutionary. NO mediates its regulatory vasorelaxing effects through guanilyl cyclase activation.
17.2: Chemical Defenses - Biology LibreTexts
WebDec 1, 2003 · Direct metabolic injury, changes in vascular reactivity, and accumulating endothelial injury each play a role in the pathogenesis of complications observed in patients with IGT. However, the relative contributions of each of these mechanisms is probably different for each complication. WebThe “local control” mechanisms operating in the ocular circulations are difficult to define. Based on more accessible circulations in other tissues, probable local control mechanisms in the eye include vascular responses linked to nearby tissue metabolism (e.g., reactive hyperemia, functional hyperemia and autoregulation), transmural pressure (e.g., myogenic … hidden treasures of egypt
Flow-Mediated Dilation Test - an overview ScienceDirect Topics
WebNov 29, 2004 · Reactive hyperemia is a complex response that reflects dilation of microvessels by non–endothelium-dependent vasodilators generated during local ischemia, including adenosine. 17 In addition, there is growing recognition that endothelium-derived nitric oxide contributes to reactive hyperemia, as evidenced by reductions in both the … WebAug 12, 2013 · After ischemia caused by temporary arterial occlusion, there is significant vasodilation and a rapid marked increase in blood flow in most tissues, including the … Webhave reported that local reactive vas- odilation can follow the initial vaso- constriction response (2-4.6). This reactive vasodilation would cause an increase in local blood volume and, coupled with the increase in local capillary permeability which is part of the inflammatory process associ- ated with tissue trauma, would sig- howell ford mer rouge la